Thin Layer Chromatographic Analysis of Beta-Lactam Antibiotics
Purpose: The paper describes some thin layer chromatographic procedures that allow simple and rapid separation and identification of penicillins and cephalosporins from complex mixtures. Methods: Using silicagel GF254 as stationary phase and selecting different mobile phases we succeeded in the sepa...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Book |
| Published: |
Tabriz University of Medical Sciences,
2013-08-01T00:00:00Z.
|
| Subjects: | |
| Online Access: | Connect to this object online. |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
MARC
| LEADER | 00000 am a22000003u 4500 | ||
|---|---|---|---|
| 001 | doaj_665d38eb97d2493aadc66c8c96b0c7e4 | ||
| 042 | |a dc | ||
| 100 | 1 | 0 | |a Gabriel Hancu |e author |
| 700 | 1 | 0 | |a Brigitta Simon |e author |
| 700 | 1 | 0 | |a Hajnal Kelemen |e author |
| 700 | 1 | 0 | |a Aura Rusu |e author |
| 700 | 1 | 0 | |a Eleonora Mircia |e author |
| 700 | 1 | 0 | |a Árpád Gyéresi |e author |
| 245 | 0 | 0 | |a Thin Layer Chromatographic Analysis of Beta-Lactam Antibiotics |
| 260 | |b Tabriz University of Medical Sciences, |c 2013-08-01T00:00:00Z. | ||
| 500 | |a 10.5681/apb.2013.059 | ||
| 500 | |a 2228-5881 | ||
| 500 | |a 2251-7308 | ||
| 520 | |a Purpose: The paper describes some thin layer chromatographic procedures that allow simple and rapid separation and identification of penicillins and cephalosporins from complex mixtures. Methods: Using silicagel GF254 as stationary phase and selecting different mobile phases we succeeded in the separation of the studied beta-lactamins. Our aim was not only to develop a simple, rapid and efficient method for their separation but also the optimization of the analytical conditions. Results: No system will separate all the beta-lactams, but they could be identified when supplementary information is used from color reactions and/or by using additional chromatographic systems. Conclusions: The right combination of solvent system and detection method allows the identification of the studied penicillins and cephalosporins and can be successfully used in the preliminary analysis beta-lactam antibiotics. | ||
| 546 | |a EN | ||
| 690 | |a Thin layer chromatography | ||
| 690 | |a Beta-lactam antibiotics | ||
| 690 | |a Penicillins | ||
| 690 | |a Cephalosporins | ||
| 690 | |a Separation | ||
| 690 | |a Therapeutics. Pharmacology | ||
| 690 | |a RM1-950 | ||
| 655 | 7 | |a article |2 local | |
| 786 | 0 | |n Advanced Pharmaceutical Bulletin, Vol 3, Iss 2, Pp 367-371 (2013) | |
| 787 | 0 | |n http://journals.tbzmed.ac.ir/PDF/APB/Manuscript/APB-3-367.pdf | |
| 787 | 0 | |n https://doaj.org/toc/2228-5881 | |
| 787 | 0 | |n https://doaj.org/toc/2251-7308 | |
| 856 | 4 | 1 | |u https://doaj.org/article/665d38eb97d2493aadc66c8c96b0c7e4 |z Connect to this object online. |