NADPH Oxidase 4: Crucial for Endothelial Function under Hypoxia-Complementing Prostacyclin

• Main Authors: Heike Brendel (Author), Jennifer Mittag (Author), Anja Hofmann (Author), Helene Hempel (Author), Sindy Giebe (Author), Patrick Diaba-Nuhoho (Author), Steffen Wolk (Author), Christian Reeps (Author), Henning Morawietz (Author), Coy Brunssen (Author)
• Format: Book
• Published: MDPI AG, 2024-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<i>Aim</i>: The primary endothelial NADPH oxidase isoform 4 (NOX4) is notably induced during hypoxia, with emerging evidence suggesting its vasoprotective role through H₂O₂ production. Therefore, we aimed to elucidate NOX4's significance...