Modeling a cataract disorder in mice with prime editing
Prime editing enables efficient introduction of targeted transversions, insertions, and deletions in mammalian cells and several organisms. However, genetic disease models with base deletions by prime editing have not yet been reported in mice. Here, we successfully generate a mouse model with a cat...
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Main Authors: | , , , , , , , , , , , |
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Format: | Book |
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Elsevier,
2021-09-01T00:00:00Z.
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A1234.567 |
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Copy 1 | Available |