Polyelectrolytes in Hot Melt Extrusion: A Combined Solvent-Based and Interacting Additive Technique for Solid Dispersions

• Главные авторы: Felix Ditzinger (Автор), Catherine Dejoie (Автор), Dubravka Sisak Jung (Автор), Martin Kuentz (Автор)
• Формат: ‌
• Опубликовано: MDPI AG, 2019-04-01T00:00:00Z.
• Предметы: article
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Solid dispersions are important supersaturating formulations to orally deliver poorly water-soluble drugs. A most important process technique is hot melt extrusion but process requirements limit the choice of suitable polymers. One way around this limitation is to synthesize new polymers. However, t...