HEMOSTIMULATING PROPERTIES OF THE CONJUGATES OF GRANULOCYTE-MACROPHAGE COLONY STIMULATING FACTOR WITH ALENDRONIC ACID

• Main Authors: G. G. Shimina (Author), A. V. Bateneva (Author), E. S. Tsyplenkova (Author), S. G. Gamaley (Author), T. I. Esina (Author), E. A. Volosnikova (Author), E. D. Danilenko (Author)
• Format: Book
• Published: Volgograd State Medical University, Pyatigorsk Medical and Pharmaceutical Institute, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The aim of the work is to evaluate the hemostimulating activity of recombinant human granulocyte-macrophage colony-stimulating factor (rhGM-CSF) conjugates with alendronic acid (ALN) in the model of cytostatic myelosuppression and the dynamics of rhGM-CSF accumulation as a part of the conjugate in t...