CXCL6 Promotes Renal Interstitial Fibrosis in Diabetic Nephropathy by Activating JAK/STAT3 Signaling Pathway

• Үндсэн зохиолчид: Meng-Yao Sun (Зохиогч), Su-Juan Wang (Зохиогч), Xiao-Qin Li (Зохиогч), Yu-Li Shen (Зохиогч), Jian-Rao Lu (Зохиогч), Xin-Hui Tian (Зохиогч), Khalid Rahman (Зохиогч), Li-Jun Zhang (Зохиогч), Hua Nian (Зохиогч), Hong Zhang (Зохиогч)
• Формат: Ном
• Хэвлэсэн: Frontiers Media S.A., 2019-03-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

In this study the role of CXCL6 in diabetic nephropathy (DN) was investigated. It was found to be overexpression in DN patients and DN rat model. And the expression of fibrosis-related cytokines was consistent with the expression of CXCL6. High glucose significantly increased the proliferation of ra...