Wogonin Induces Apoptosis and Reverses Sunitinib Resistance of Renal Cell Carcinoma Cells via Inhibiting CDK4-RB Pathway

• Үндсэн зохиолчид: Yong Wang (Зохиогч), Shouzhen Chen (Зохиогч), Shuna Sun (Зохиогч), Guangyi Liu (Зохиогч), Lipeng Chen (Зохиогч), Yangyang Xia (Зохиогч), Jianfeng Cui (Зохиогч), Wenfu Wang (Зохиогч), Xuewen Jiang (Зохиогч), Lei Zhang (Зохиогч), Yaofeng Zhu (Зохиогч), Yongxin Zou (Зохиогч), Benkang Shi (Зохиогч)
• Формат: Ном
• Хэвлэсэн: Frontiers Media S.A., 2020-07-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Wogonin, an active component derived from Scutellaria baicalensis, has shown anti-tumor activities in several malignancies. However, the roles of wogonin in RCC cells remain elusive. Here, we explored the effects of wogonin on RCC cells and the underlying mechanisms. We found that wogonin showed sig...