Wogonin Induces Apoptosis and Reverses Sunitinib Resistance of Renal Cell Carcinoma Cells via Inhibiting CDK4-RB Pathway

• প্রধান লেখক: Yong Wang (লেখক), Shouzhen Chen (লেখক), Shuna Sun (লেখক), Guangyi Liu (লেখক), Lipeng Chen (লেখক), Yangyang Xia (লেখক), Jianfeng Cui (লেখক), Wenfu Wang (লেখক), Xuewen Jiang (লেখক), Lei Zhang (লেখক), Yaofeng Zhu (লেখক), Yongxin Zou (লেখক), Benkang Shi (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Frontiers Media S.A., 2020-07-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Wogonin, an active component derived from Scutellaria baicalensis, has shown anti-tumor activities in several malignancies. However, the roles of wogonin in RCC cells remain elusive. Here, we explored the effects of wogonin on RCC cells and the underlying mechanisms. We found that wogonin showed sig...