Profiling patent compounds in lipid nanoparticle formulations of siRNA

• Main Authors: Yunfeng Han (Author), Mengyang Wang (Author), Yu Chen (Author), Defang Ouyang (Author), Ying Zheng (Author), Yuanjia Hu (Author)
• Format: Book
• Published: Elsevier, 2024-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Lipid nanoparticles (LNPs) have emerged as a prominent delivery system for nucleic acid drugs, attracting significant attention, especially through the successful development of several commercial products. As a key component in LNPs, cationic lipids have long served as a key technical barrier to bl...