Solubility, Antioxidation, and Oral Bioavailability Improvement of Mangiferin Microparticles Prepared Using the Supercritical Antisolvent Method

• Main Authors: Mengran Liu (Author), Yankun Liu (Author), Yunlong Ge (Author), Zhaoliang Zhong (Author), Zijian Wang (Author), Tong Wu (Author), Xiuhua Zhao (Author), Yuangang Zu (Author)
• Format: Book
• Published: MDPI AG, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In view of the poor water solubility and low oral bioavailability of mangiferin (MG), in this study, the supercritical antisolvent (SAS) technology was used to prepare mangiferin microparticles (MG MPs) with <i>N</i>,<i>N</i>-dimethylformamide (DMF) as solvent and carbon diox...