Cerebral Oxidative Stress in Early Alzheimer's Disease Evaluated by ⁶⁴Cu-ATSM PET/MRI: A Preliminary Study

• Main Authors: Hidehiko Okazawa (Author), Masamichi Ikawa (Author), Tetsuya Tsujikawa (Author), Tetsuya Mori (Author), Akira Makino (Author), Yasushi Kiyono (Author), Yasunari Nakamoto (Author), Hirotaka Kosaka (Author), Makoto Yoneda (Author)
• Format: Book
• Published: MDPI AG, 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Oxidative stress imaging using diacetyl-bis (<i>N</i>⁴-methylthiosemicarbazone) (Cu-ATSM) was applied to the evaluation of patients with early Alzheimer's disease (eAD). Ten eAD patients (72 ± 9 years) and 10 age-matched healthy controls (HCs) (73 ± 9 years) p...