Predominantly Pro-Inflammatory Phenotype with Mixed M1/M2 Polarization of Peripheral Blood Classical Monocytes and Monocyte-Derived Macrophages among Patients with Excessive Ethanol Intake

• Главные авторы: María Fernández-Regueras (Автор), Cristina Carbonell (Автор), Daniel Salete-Granado (Автор), Juan-Luis García (Автор), Marcos Gragera (Автор), María-Ángeles (Автор), Francisco-Javier (Автор), Andrea Mayado (Автор), Jorge-Luis Torres (Автор), Luis-Antonio Corchete (Автор), Ricardo Usategui-Martín (Автор), Elena Bueno-Martínez (Автор), Maura Rojas-Pirela (Автор), Guadalupe Sabio (Автор), Rogelio González-Sarmiento (Автор), Alberto Orfao (Автор), Francisco-Javier Laso (Автор), Julia Almeida (Автор), Miguel Marcos (Автор)
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• Опубликовано: MDPI AG, 2023-09-01T00:00:00Z.
• Предметы: article
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Excessive alcohol consumption impairs the immune system, induces oxidative stress, and triggers the activation of peripheral blood (PB) monocytes, thereby contributing to alcoholic liver disease (ALD). We analyzed the M1/M2 phenotypes of circulating classical monocytes and macrophage-derived monocyt...