Synthesis and antitumor activity of 1,3,4-oxadiazole substituted 2-(5-ylidene-2,4-dioxothiazolidin-3-yl)-acetamides

• Main Authors: Maryan Lelyukh (Author), Myroslava Kalytovska (Author), Marta Zastryzhna (Author), Arkadii Savchenko (Author), Ihor Chaban (Author), Stefan Harkov (Author)
• Format: Book
• Published: Pensoft Publishers, 2023-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A series of novel 1,3,4-oxadiazole substituted 2-(5-aryl/heterylidene-2,4-dioxothiazolidine-3-ylidene)-acetamides and their 5-unsubstituted analogues have been synthesized following N-alkylation reaction of 2-chloro-N-(5-aryl-[1,3,4]oxadiazol-2-yl)-acetamides with thiazolidinedione and potassium sal...