The biophysical principles underpinning muco-trapping functions of antibodies

• المؤلفون الرئيسيون: Alison Schaefer (مؤلف), Samuel K. Lai (مؤلف)
• التنسيق: كتاب
• منشور في: Taylor & Francis Group, 2022-04-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

In addition to the classical immunological functions such as neutralization, antibody-dependent cellular cytotoxicity, and complement activation, IgG antibodies possess a little-recognized and under-utilized effector function at mucosal surfaces: trapping pathogens in mucus. IgG can potently immobil...