"Computational Analysis of the Effect of fbn1 Gene Mutations in the Marfan Syndrome"
Fibrillin is a large glycoprotein synthesized in the tissues involved in Marfan syndrome, and known to be involved in tissue elasticity. The syndrome is corresponded to fbn1 gene and is characterized by cardiovascular, ocular, and skeletal abnormalities. N-terminus of fibrillin 1 binds to microfibri...
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Tehran University of Medical Sciences,
2004-07-01T00:00:00Z.
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