Altered vector competence in an experimental mosquito-mouse transmission model of Zika infection.

• Main Authors: Ryuta Uraki (Author), Andrew K Hastings (Author), Andrea Gloria-Soria (Author), Jeffrey R Powell (Author), Erol Fikrig (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2018-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Few animal models of Zika virus (ZIKV) infection have incorporated arthropod-borne transmission. Here, we establish an Aedes aegypti mosquito model of ZIKV infection of mice, and demonstrate altered vector competency among three strains, (Orlando, ORL, Ho Chi Minh, HCM, and Patilas, PAT). All strain...