Synthesis of chiral pyrazolo[4,3-e][1,2,4]triazine sulfonamides with tyrosinase and urease inhibitory activity

• Main Authors: Mariusz Mojzych (Author), Paweł Tarasiuk (Author), Katarzyna Kotwica-Mojzych (Author), Muhammad Rafiq (Author), Sung-Yum Seo (Author), Michał Nicewicz (Author), Emilia Fornal (Author)
• Format: Book
• Published: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A new series of sulfonamide derivatives of pyrazolo[4,3-e][1,2,4]triazine with chiral amino group has been synthesized and characterized. The compounds were tested for their tyrosinase and urease inhibitory activity. Evaluation of prepared derivatives demonstrated that compounds (8b) and (8j) are mo...