Brexpiprazole has a low risk of dopamine D2 receptor sensitization and inhibits rebound phenomena related to D2 and serotonin 5‐HT2A receptors in rats

• मुख्य लेखकों: Naoki Amada (लेखक), Hitomi Akazawa (लेखक), Yuta Ohgi (लेखक), Kenji Maeda (लेखक), Haruhiko Sugino (लेखक), Nobuyuki Kurahashi (लेखक), Tetsuro Kikuchi (लेखक), Takashi Futamura (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Wiley, 2019-12-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Abstract Background Long‐term antipsychotic treatment in patients with schizophrenia can induce supersensitivity psychosis and tardive dyskinesia which is thought to be caused by dopamine D2 receptor sensitization. We evaluated the effects of brexpiprazole on D2 receptor sensitivity after subchronic...