Metformin Impacts Human Syncytiotrophoblast Mitochondrial Function from Pregnancies Complicated by Obesity and Gestational Diabetes Mellitus in a Sexually Dimorphic Manner

Maternal obesity and gestational diabetes mellitus (GDM) are associated with placental dysfunction, small for gestational age (SGA) offspring, and programming of adult-onset disease. We examine how metformin, commonly used to treat type A2 GDM, affects placental metabolism as well as mitochondrial c...

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Main Authors: Jessica F. Hebert (Author), Leslie Myatt (Author)
Format: Book
Published: MDPI AG, 2023-03-01T00:00:00Z.
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3rd Floor Main Library

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