Modeling Pharmacokinetics in Individual Patients Using Therapeutic Drug Monitoring and Artificial Population Quasi-Models: A Study with Piperacillin

• Main Authors: Gellért Balázs Karvaly (Author), István Vincze (Author), Michael Noel Neely (Author), István Zátroch (Author), Zsuzsanna Nagy (Author), Ibolya Kocsis (Author), Csaba Kopitkó (Author)
• Format: Book
• Published: MDPI AG, 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Population pharmacokinetic (pop-PK) models constructed for model-informed precision dosing often have limited utility due to the low number of patients recruited. To augment such models, an approach is presented for generating fully artificial quasi-models which can be employed to make individual es...