Neuroprotective effects of pramipexole transdermal patch in the MPTP-induced mouse model of Parkinson's disease

• Main Authors: Yaozhen Wang (Author), Xiaofeng Yu (Author), Ping Zhang (Author), Yinglin Ma (Author), Lei Wang (Author), Huali Xu (Author), Dayun Sui (Author)
• Format: Book
• Published: Elsevier, 2018-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Parkinson's disease (PD) is characterized by the selective death of dopaminergic neurons. To avoid inconvenience of frequent administration caused by short half life and recurrence of symptoms such as tremor and bradykinesia incurred by drug elimination, a novel long-acting pramipexole transder...