Preparation of Topical Itraconazole with Enhanced Skin/Nail Permeability and In Vivo Antifungal Efficacy against Superficial Mycosis

• मुख्य लेखकों: Laxman Subedi (लेखक), Seung-Yub Song (लेखक), Saurav Kumar Jha (लेखक), Sung-Ho Lee (लेखक), Rudra Pangeni (लेखक), Kyo-Tan Koo (लेखक), Beum Joon Kim (लेखक), Seung-Sik Cho (लेखक), Jin Woo Park (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2021-04-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

In this study, a stable and highly skin-permeable topical delivery system for itraconazole (ITZ) was designed to provide effective treatment against superficial mycosis. Herein, ITZ was incorporated into a solution composed of ethanol, benzyl alcohol, hydrochloric acid, Transcutol P, and cyclomethic...