Chaperoning to the metabolic party: The emerging therapeutic role of heat-shock proteins in obesity and type 2 diabetes

• Main Authors: Darren C. Henstridge (Author), Martin Whitham (Author), Mark A. Febbraio (Author)
• Format: Knjiga
• Izdano: Elsevier, 2014-11-01T00:00:00Z.
• Teme: article
• Online dostop: Connect to this object online.

Background: From their initial, accidental discovery 50 years ago, the highly conserved Heat Shock Proteins (HSPs) continue to exhibit fundamental roles in the protection of cell integrity. Meanwhile, in the midst of an obesity epidemic, research demonstrates a key involvement of low grade inflammat...