Subnanomolar indazole-5-carboxamide inhibitors of monoamine oxidase B (MAO-B) continued: indications of iron binding, experimental evidence for optimised solubility and brain penetration

Pharmacological and physicochemical studies of N-unsubstituted indazole-5-carboxamides (subclass I) and their structurally optimised N1-methylated analogues (subclass II), initially developed as drug and radioligand candidates for the treatment and diagnosis of Parkinson's disease (PD), are pre...

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Hoofdauteurs: Nikolay T. Tzvetkov (Auteur), Liudmil Antonov (Auteur)
Formaat: Boek
Gepubliceerd in: Taylor & Francis Group, 2017-01-01T00:00:00Z.
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3rd Floor Main Library

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