A Comparative Effectiveness Study of Newborn Screening Methods for Four Lysosomal Storage Disorders

• Main Authors: Karen A. Sanders (Author), Dimitar K. Gavrilov (Author), Devin Oglesbee (Author), Kimiyo M. Raymond (Author), Silvia Tortorelli (Author), John J. Hopwood (Author), Fred Lorey (Author), Ramanath Majumdar (Author), Charles A. Kroll (Author), Amber M. McDonald (Author), Jean M. Lacey (Author), Coleman T. Turgeon (Author), Justin N. Tucker (Author), Hao Tang (Author), Robert Currier (Author), Grazia Isaya (Author), Piero Rinaldo (Author), Dietrich Matern (Author)
• Format: Book
• Published: MDPI AG, 2020-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Newborn screening for one or more lysosomal disorders has been implemented in several US states, Japan and Taiwan by multiplexed enzyme assays using either tandem mass spectrometry or digital microfluidics. Another multiplex assay making use of immunocapture technology has also been proposed. To inv...