A National Strategy to Develop Pragmatic Clinical Trials Infrastructure

• Main Authors: Thomas W. Concannon (Author), Jeanne‐Marie Guise (Author), Rowena J. Dolor (Author), Paul Meissner (Author), Sean Tunis (Author), Jerry A. Krishnan (Author), Wilson D. Pace (Author), Joel Saltz (Author), William R. Hersh (Author), Lloyd Michener (Author), Timothy S. Carey (Author)
• פורמט: ספר
• יצא לאור: Wiley, 2014-04-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Abstract An important challenge in comparative effectiveness research is the lack of infrastructure to support pragmatic clinical trials, which compare interventions in usual practice settings and subjects. These trials present challenges that differ from those of classical efficacy trials, which ar...