Cyclooxygenase-2: A Role in Cancer Stem Cell Survival and Repopulation of Cancer Cells during Therapy

Cyclooxygenase-2 (COX-2) is an inducible form of the enzyme that catalyses the synthesis of prostanoids, including prostaglandin E2 (PGE2), a major mediator of inflammation and angiogenesis. COX-2 is overexpressed in cancer cells and is associated with progressive tumour growth, as well as resistanc...

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Bibliographic Details
Main Authors: Lisa Y. Pang (Author), Emma A. Hurst (Author), David J. Argyle (Author)
Format: Book
Published: Hindawi Limited, 2016-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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