Bioactive PI3-kinase/Akt/mTOR Inhibitors in Targeted Lung Cancer Therapy

• Main Authors: Somayyeh Ghareghomi (Author), Vahideh Atabaki (Author), Naseh Abdollahzadeh (Author), Shahin Ahmadian (Author), Salar Hafez Ghoran (Author)
• Format: Book
• Published: Tabriz University of Medical Sciences, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

One of the central signaling pathways with a regulatory effect on cell proliferation and survival is Akt/mTOR. In many human cancer types, for instance, lung cancer, the overexpression of Akt/mTOR has been reported. For this reason, either targeting cancer cells by synthetic or natural products affe...