Design, synthesis, and biological investigation of selective human carbonic anhydrase II, IX, and XII inhibitors using 7-aryl/heteroaryl triazolopyrimidines bearing a sulfanilamide scaffold

A novel library of human carbonic anhydrase (hCA) inhibitors based on the 2-sulfanilamido[1,2,4]triazolo[1,5-a]pyrimidine skeleton modified at its 7-position was prepared by an efficient convergent procedure. These derivatives were evaluated in vitro for their inhibition properties against a represe...

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Main Authors: Romeo Romagnoli (Author), Tiziano De Ventura (Author), Stefano Manfredini (Author), Erika Baldini (Author), Claudiu T. Supuran (Author), Alessio Nocentini (Author), Andrea Brancale (Author), Carmine Varricchio (Author), Roberta Bortolozzi (Author), Lorenzo Manfreda (Author), Giampietro Viola (Author)
Format: Book
Published: Taylor & Francis Group, 2023-12-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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