Expression of factor XIII originating from synovial fibroblasts and macrophages induced by interleukin-6 signaling

• Main Authors: Hirofumi Watanabe (Author), Sho Mokuda (Author), Tadahiro Tokunaga (Author), Hiroki Kohno (Author), Michinori Ishitoku (Author), Kei Araki (Author), Tomohiro Sugimoto (Author), Yusuke Yoshida (Author), Toshihiro Yamamoto (Author), Mayuko Matsumoto (Author), Junya Masumoto (Author), Shintaro Hirata (Author), Eiji Sugiyama (Author)
• Format: Book
• Published: BMC, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Blood coagulation factor XIII (FXIII) promotes cross-linking between fibrin molecules at the final stage of the blood coagulation cascade. However, its expression in cells or tissues and function, particularly factor XIII subunit B (FXIII-B), remains controversial. Hemorrhagic FX...