Immune Modulation as an Effective Adjunct Post-exposure Therapeutic for B. pseudomallei.

• Main Authors: William J Wilson (Author), Maryam F Afzali (Author), Jason E Cummings (Author), Marie E Legare (Author), Ronald B Tjalkens (Author), Christopher P Allen (Author), Richard A Slayden (Author), William H Hanneman (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2016-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Melioidosis is caused by the facultative intracellular bacterium Burkholderia pseudomallei and is potentially fatal. Despite a growing global burden and high fatality rate, little is known about the disease. Recent studies demonstrate that cyclooxygenase-2 (COX-2) inhibition is an effective post-exp...