Development and Characterization of Solid Dispersion for Dissolution Improvement of Furosemide by Cogrinding Method

• Main Authors: Mohammad Reza Siahi-Shadbad (Author), Saeed Ghanbarzadeh (Author), Mohammad Barzegar-Jalali (Author), Hadi Valizadeh (Author), Alireza Taherpoor (Author), Ghobad Mohammadi (Author), Azim Barzegar-Jalali (Author), Khosro Adibkia (Author)
• Format: Book
• Published: Tabriz University of Medical Sciences, 2014-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose: The purpose of this study was to prepare and characterize solid dispersion formulation of furosemide to enhance dissolution rate. Methods: Solid dispersions with different drug: carrier ratios were prepared by cogrinding method using crospovidone and microcrystalline cellulose as carrier. T...