Granisetron attenuates liver injury and inflammation in a rat model of cecal ligation and puncture-induced sepsis

Background and aims: Sepsis induced liver injury is recognized as a serious complication in intensive care units, it is deeply associated with oxidative stress, inflammation and subsequent pyroptosis. Hepatic pyroptosis known to aggravate sepsis-induced liver injury. Previous studies proved that gra...

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Autores principales: Amira M. Aboyoussef (Autor), Mostafa Kamal Mohammad (Autor), Ali Ahmed Abo-Saif (Autor), Basim A.S. Messiha (Autor)
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Publicado: Elsevier, 2021-12-01T00:00:00Z.
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