Suppression of Autoimmune Arthritis by Small Molecule Inhibitors of the JAK/STAT Pathway
A skewed ratio of pro-inflammatory to anti-inflammatory cytokines, elevated growth factor synthesis and T- and B-lymphocyte activation are 3 hallmarks of rheumatoid arthritis (RA) pathology. Interleukin-6 (IL-6), IL-7, IL-17, IL-12/IL-23 and growth factors, granulocyte macrophage-colony stimulating...
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MDPI AG,
2010-05-01T00:00:00Z.
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