Cell membrane components of Brucella melitensis play important roles in the resistance of low-level rifampicin.

• Main Authors: Xiaowen Yang (Author), Tonglei Wu (Author), Wenxiao Liu (Author), Guozhong Tian (Author), Hongyan Zhao (Author), Dongri Piao (Author), Hai Jiang (Author), Qingmin Wu (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Brucella spp. are facultative intracellular pathogens that can persistently colonize host cells and cause the zoonosis- brucellosis. The WHO recommended a treatment for brucellosis that involves a combination of doxycycline, rifampicin, or streptomycin. The aim of this study was to screen rifampicin...