Resolving inherited and de novo germline predisposing sequence variants by means of whole exome trio analyses in childhood hematological malignancies

• Glavni autori: Triantafyllia Brozou (Autor), Layal Yasin (Autor), Danielle Brandes (Autor), Daniel Picard (Autor), Carolin Walter (Autor), Julian Varghese (Autor), Martin Dugas (Autor), Ute Fischer (Autor), Arndt Borkhardt (Autor), Oskar A. Haas (Autor)
• Format: Knjiga
• Izdano: Frontiers Media S.A., 2023-02-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Molecular screening tools have significantly eased the assessment of potential germline susceptibility factors that may underlie the development of pediatric malignancies. Most of the hitherto published studies utilize the comparative analyses of the respective patients' germline and tumor tiss...