Vaccination with Leishmania infantum acidic ribosomal P0 but not with nucleosomal histones proteins controls Leishmania infantum infection in hamsters.

• Main Authors: Lais Pereira (Author), Melissa Abbehusen (Author), Clarissa Teixeira (Author), Jurema Cunha (Author), Ivan P Nascimento (Author), Kyioshi Fukutani (Author), Washington dos-Santos (Author), Aldina Barral (Author), Camila Indiani de Oliveira (Author), Manoel Barral-Netto (Author), Manoel Soto (Author), Cláudia Ida Brodskyn (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2015-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND: Several intracellular Leishmania antigens have been identified in order to find a potential vaccine capable of conferring long lasting protection against Leishmania infection. Histones and Acid Ribosomal proteins are already known to induce an effective immune response and have successfu...