The Potential Protective Role of Naringenin against Dasatinib-Induced Hepatotoxicity

• Hauptverfasser: Ahmed Z. Alanazi (Verfasst von), Khalid Alhazzani (Verfasst von), Salah Q. Alrewily (Verfasst von), Khaldoon Aljerian (Verfasst von), Mohammad M. Algahtani (Verfasst von), Qamraa H. Alqahtani (Verfasst von), Dhanush Haspula (Verfasst von), Abdullah S. Alhamed (Verfasst von), Mohammed Alqinyah (Verfasst von), Mohammad Raish (Verfasst von)
• Format: Buch
• Veröffentlicht: MDPI AG, 2023-06-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Dasatinib (DASA) is a novel tyrosine kinase inhibitor, approved for leukemia treatment. However, the long-term use of DASA induces several complications, especially liver damage. On the other hand, Naringenin (NGN) is a potent antioxidant and anti-inflammatory agent which is known to exert protectiv...