In silico estrogen receptor alpha antagonist studies and toxicity prediction of Melia azedarach leaves bioactive ethyl acetate fraction

• Main Authors: Martha Ervina (Author), Mohammad Rizki Fadhil Pratama (Author), Hadi Poerwono (Author), Juni Ekowati (Author), Retno Widyowati (Author), Katsuyoshi Matsunami (Author), Sukardiman (Author)
• Format: Book
• Published: Wolters Kluwer Medknow Publications, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The estrogen hormone dependent accounts for a major cause in the incidence of women breast cancer. Thus, their receptor, especially the estrogen receptor α (ER-α), is becoming a target in endocrine treatment. These ligand-inducible nuclear functions are regulated by an array of phytochemical and syn...