Synthesis, in silico modelling, and in vitro biological evaluation of substituted pyrazole derivatives as potential anti-skin cancer, anti-tyrosinase, and antioxidant agents

• Main Authors: Samuel T. Boateng (Author), Tithi Roy (Author), Kara Torrey (Author), Uchechi Owunna (Author), Sergette Banang-Mbeumi (Author), David Basnet (Author), Eleonora Niedda (Author), Alexis D. Alexander (Author), Denzel El Hage (Author), Siriki Atchimnaidu (Author), Bolni Marius Nagalo (Author), Dinesh Aryal (Author), Ann Findley (Author), Navindra P. Seeram (Author), Tatiana Efimova (Author), Mario Sechi (Author), Ronald A. Hill (Author), Hang Ma (Author), Jean Christopher Chamcheu (Author), Siva Murru (Author)
• Format: Book
• Published: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Twenty-five azole compounds (P1-P25) were synthesised using regioselective base-metal catalysed and microwave-assisted approaches, fully characterised by high-resolution mass spectrometry (HRMS), nuclear magnetic resonance (NMR), and infrared spectra (IR) analyses, and evaluated for anticancer, anti...