Network pharmacology integrated with experimental validation to elucidate the mechanisms of action of the Guizhi-Gancao Decoction in the treatment of phenylephrine-induced cardiac hypertrophy

• Main Authors: Kaijing Yang (Author), Xiaoli Shan (Author), Yang Songru (Author), Mengwei Fu (Author), Pei Zhao (Author), Wei Guo (Author), Ming Xu (Author), Huihua Chen (Author), Rong Lu (Author), Chen Zhang (Author)
• Format: Book
• Published: Taylor & Francis Group, 2024-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

AbstractContext The mechanisms of Traditional Chinese Medicine (TCM) Guizhi-Gancao Decoction (GGD) remain unknown.Objective This study explores the mechanisms of GGD against cardiac hypertrophy.Materials and methods Network pharmacology analysis was carried out to identify the potential targets of G...