An immunoinformatic approach to assessing the immunogenic capacity of alpha-neurotoxins in elapid snake venoms

• Главные авторы: Yi Wei Chan (Автор), Choo Hock Tan (Автор), Choon Han Heh (Автор), Kae Yi Tan (Автор)
• Формат: ‌
• Опубликовано: Frontiers Media S.A., 2023-04-01T00:00:00Z.
• Предметы: article
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Introduction: Most elapid snakes produce venoms that contain alpha-neurotoxins (α-NTXs), which are proteins that cause post-synaptic blockade and paralysis in snakebite envenoming. However, existing elapid antivenoms are known for their low potency in neutralizing the neurotoxic activity of α-NTXs,...