Gas chromatography-mass spectrometry method for determination of β-propiolactone in human inactivated rabies vaccine and its hydrolysis analysis

A simple method was established for the determination of β-propiolactone (BPL) in human inactivated rabies vaccine by gas chromatography-mass spectrometry (GC-MS). The determination was performed on an Agilent HP-INNOWAX (30 m × 0.32 mm i.d., 0.25 µm) capillary column at the temperature of 80 °C. El...

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Main Authors: Shuo Lei (Author), Xun Gao (Author), Yang Sun (Author), Xiangyong Yu (Author), Longshan Zhao (Author)
Format: Book
Published: Elsevier, 2018-12-01T00:00:00Z.
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