A method for determining potential parental contamination: linkage disequilibrium-based log-likelihood ratio analysis for IVF-PGT

• Main Authors: Le Bo (Author), Fangfang Dong (Author), Zhinan Wu (Author), Anwen Zhou (Author), Yulan Zhang (Author), Lingyin Kong (Author), Lei Zhan (Author), Naru Lu (Author), Lina Qi (Author), Tingting Sun (Author), Bo Liang (Author), Caiping Mao (Author)
• Format: Book
• Published: BMC, 2024-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background At present, embryologists are attempting to use conventional in vitro fertilization (cIVF) as an alternative to intracytoplasmic sperm injection (ICSI) for preimplantation genetic testing (PGT). However, the potential parental contamination origin of sperm cells and cumulus cells...