Safe CRISPR-Cas9 Inhibition of HIV-1 with High Specificity and Broad-Spectrum Activity by Targeting LTR NF-κB Binding Sites

Safe CRISPR-Cas9 Inhibition of HIV-1 with High Specificity and Broad-Spectrum Activity by Targeting LTR NF-κB Binding Sites

Viral latency of human immunodeficiency virus type 1 (HIV-1) has become a major hurdle to a cure in the highly effective antiretroviral therapy (ART) era. The clustered regularly interspaced short palindromic repeats (CRISPR)-Cas9 system has successfully been demonstrated to excise or inactivate int...

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Main Authors: Cheng-Han Chung (Author), Alexander G. Allen (Author), Andrew J. Atkins (Author), Neil T. Sullivan (Author), Greg Homan (Author), Robert Costello (Author), Rebekah Madrid (Author), Michael R. Nonnemacher (Author), Will Dampier (Author), Brian Wigdahl (Author)
Format: Book
Published: Elsevier, 2020-09-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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