pH Responsive Polymer Micelles Enhances Inhibitory Efficacy on Metastasis of Murine Breast Cancer Cells

• Main Authors: Jie Wang (Author), Gejing De (Author), Qiaoxin Yue (Author), Hai Ma (Author), Jintang Cheng (Author), Guangwei Zhu (Author), Maobo Du (Author), Hong Yi (Author), Qinghe Zhao (Author), Yanjun Chen (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A pH sensitive micellar cargo was fabricated for pH triggered delivery of hydrophobic drug paclitaxel with pH controlled drug release profiles. The size, drug loading content, and encapsulation efficiency of PTX loaded micelles were 20-30 nm, 7.5%, 82.5%, respectively. PTX loaded PELA-PBAE micelles...