Leupaxin promotes hepatic gluconeogenesis and glucose metabolism by coactivation with hepatic nuclear factor 4α

• Main Authors: Xiaomin Luo (Author), Fang Liu (Author), Lijun Zhu (Author), Caizhi Liu (Author), Ruhui Shen (Author), Xiaoyin Ding (Author), Yufan Wang (Author), Xiaofang Tang (Author), Yongde Peng (Author), Zhijian Zhang (Author)
• Format: Book
• Published: Elsevier, 2025-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: As the primary source of glucose during fasting, hepatic gluconeogenesis is rigorously regulated to maintain euglycemia. Abnormal gluconeogenesis in the liver can lead to hyperglycemia, a key diagnostic marker and the primary pathological contributor to type 2 diabetes (T2D) and metaboli...