Low-Affinity NMDA Receptor Antagonist Hemantane in a Topical Formulation Attenuates Arthritis Induced by Freund's Complete Adjuvant in Rats

• Hoofdauteurs: Elena Ivanova (Auteur), Alexander Matyushkin (Auteur), Alexandra Sorokina (Auteur), Svetlana Alexeeva (Auteur), Irina Miroshkina (Auteur), Kirill Kachalov (Auteur), Tatyana Voronina (Auteur), Andrey Durnev (Auteur)
• Formaat: Boek
• Gepubliceerd in: Tabriz University of Medical Sciences, 2024-03-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Purpose: N-methyl-D-aspartate (NMDA) receptors that are expressed by T-cells modulate T-cell proliferation, cytotoxicity and cell migration toward chemokines. Several studies have shown an anti-inflammatory effect of NMDA receptor antagonists. This study compares the effect of the noncompetitive low...