The Effect of Adenosine A2A and A2B Antagonists on Tracheal Responsiveness, Serum Levels of Cytokines and Lung Inflammation in Guinea Pig Model of Asthma

• Main Authors: Laleh Pejman (Author), Hasan Omrani (Author), Zahra Mirzamohammadi (Author), Amir Ali Shahbazfar (Author), Majid Khalili (Author), Rana Keyhanmanesh (Author)
• Format: Book
• Published: Tabriz University of Medical Sciences, 2014-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose: Nowadays adenosine is specified as an important factor in the pathophysiology of asthma. For determining the effect of different A2 receptors, in this investigation the effect of single dose of selective adenosine A2A and A2B antagonists (ZM241385 and MRS1706) on different inflammatory para...