Sphingosine 1-Phosphate Receptor 1 as a Useful Target for Treatment of Multiple Sclerosis
Sphingosine 1-phosphate (S1P), a lysophospholipid mediator, is generated from sphingosine by sphingosine kinases and binds five known cell surface receptors. S1P receptor 1 (S1P<sub>1</sub>) plays an essential role in lymphocyte egress from secondary lymphoid organs (SLO), as evinced by...
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Format: | Book |
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MDPI AG,
2012-05-01T00:00:00Z.
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A1234.567 |
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