Assessing the immunogenicity risk of salmon calcitonin peptide impurities using in silico and in vitro methods

• Main Authors: Brian J. Roberts (Author), Aimee E. Mattei (Author), Kristina E. Howard (Author), James L. Weaver (Author), Hao Liu (Author), Sandra Lelias (Author), William D. Martin (Author), Daniela Verthelyi (Author), Eric Pang (Author), Katie J. Edwards (Author), Anne S. De Groot (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Advances in synthetic peptide synthesis have enabled rapid and cost-effective peptide drug manufacturing. For this reason, peptide drugs that were first produced using recombinant DNA (rDNA) technology are now being produced using solid- and liquid-phase peptide synthesis. While peptide synthesis ha...